Linked Life Data

2851760

Source:http://linkedlifedata.com/resource/pubmed/id/2851760

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1989-3-17
pubmed:abstractText
Two hundred and thirty patients with histologically proven small cell lung cancer--133 patients with limited disease and 97 patients with extensive disease--were treated from 1979 to 1986 in 3 prospective clinical trials at a single institution. Univariate and multivariate statistical analyses (Cox-models) were used to determine whether pretherapeutic factors can be used to predict survival and long-term survival. Extent of disease, determined by pretherapeutic staging, turned out to be the most significant prognostic parameter. Survival beyond 2 years was almost exclusively confined to patients with limited disease. Further independent predictors of survival duration in patients with limited disease were serum levels of lactate dehydrogenase and urea. In extensive disease, however, performance status, levels of serum lactate dehydrogenase and the intensity of therapy turned out to be the best pretherapeutic prognostic factors.
pubmed:language
ger
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0378-584X
pubmed:author
pubmed:issnType
Print
pubmed:volume
11 Suppl 2
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
34-40
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
[Pretherapeutic prognostic factors in small cell bronchial cancer].
pubmed:affiliation
Innere Universitätsklinik und Poliklinik (Tumorforschung), Essen.
pubmed:publicationType
Journal Article, English Abstract