|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
11
|
|
pubmed:dateCreated |
1989-2-23
|
|
pubmed:abstractText |
We have studied the cis and trans interactions of the alpha- and beta-globin genes in a transient expression system. We found that the alpha-globin gene inhibited beta-globin expression in cis but not in trans. The silencer element responsible for this inhibition was localized to a 259-base-pair fragment at the 5' end of the alpha-globin gene.
|
|
pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/2850473-2828925,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2850473-2835225,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2850473-2987809,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2850473-3010279,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2850473-3296191,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2850473-3478680,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2850473-3691478,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2850473-3888409,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2850473-4931680,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2850473-6088069,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2850473-6188062,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2850473-6200874,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2850473-6205764,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2850473-6277501,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2850473-6290076,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2850473-6363938,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2850473-6856467
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Nov
|
|
pubmed:issn |
0270-7306
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
8
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
5047-51
|
|
pubmed:dateRevised |
2010-11-18
|
|
pubmed:meshHeading |
pubmed-meshheading:2850473-Enhancer Elements, Genetic,
pubmed-meshheading:2850473-Gene Expression Regulation,
pubmed-meshheading:2850473-Genes, Regulator,
pubmed-meshheading:2850473-Genetic Linkage,
pubmed-meshheading:2850473-Globins,
pubmed-meshheading:2850473-HeLa Cells,
pubmed-meshheading:2850473-Humans,
pubmed-meshheading:2850473-Multigene Family,
pubmed-meshheading:2850473-Simian virus 40
|
|
pubmed:year |
1988
|
|
pubmed:articleTitle |
A silencer element from the alpha-globin gene inhibits expression of beta-like genes.
|
|
pubmed:affiliation |
Department of Medicine, University of Michigan School of Medicine, Ann Arbor.
|
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.
|
