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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
13
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pubmed:dateCreated |
1989-2-16
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pubmed:abstractText |
The effects of lipoxygenase products (5-, 12-, 15-HETE, LTB4) and superoxide radicals on human colonic (Na+ + K+)-ATPase and specific ouabain binding were measured. No significant inhibition in concentrations up to 3 x 10(-5) M was observed. The results are discussed with regard to a possible role of lipoxygenase products and radicals in the pathogenesis of water and electrolyte disturbances in various diarrheal states including inflammatory bowel disease.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/12-Hydroxy-5,8,10,14-eicosatetraenoi...,
http://linkedlifedata.com/resource/pubmed/chemical/15-hydroxy-5,8,11,13-eicosatetraenoi...,
http://linkedlifedata.com/resource/pubmed/chemical/5-hydroxy-6,8,11,14-eicosatetraenoic...,
http://linkedlifedata.com/resource/pubmed/chemical/Free Radicals,
http://linkedlifedata.com/resource/pubmed/chemical/Hydroxyeicosatetraenoic Acids,
http://linkedlifedata.com/resource/pubmed/chemical/Leukotriene B4,
http://linkedlifedata.com/resource/pubmed/chemical/Lipoxygenase,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Drug,
http://linkedlifedata.com/resource/pubmed/chemical/Sodium-Potassium-Exchanging ATPase,
http://linkedlifedata.com/resource/pubmed/chemical/Superoxides,
http://linkedlifedata.com/resource/pubmed/chemical/cardiac glycoside receptors
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0023-2173
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
66
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
599-600
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:2850405-12-Hydroxy-5,8,10,14-eicosatetraenoic Acid,
pubmed-meshheading:2850405-Colon,
pubmed-meshheading:2850405-Free Radicals,
pubmed-meshheading:2850405-Humans,
pubmed-meshheading:2850405-Hydroxyeicosatetraenoic Acids,
pubmed-meshheading:2850405-Leukotriene B4,
pubmed-meshheading:2850405-Lipoxygenase,
pubmed-meshheading:2850405-Receptors, Drug,
pubmed-meshheading:2850405-Sodium-Potassium-Exchanging ATPase,
pubmed-meshheading:2850405-Superoxides
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pubmed:year |
1988
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pubmed:articleTitle |
Human colonic (Na+ + K+)-ATPase and specific ouabain binding are not influenced by lipoxygenase products or superoxide radicals.
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pubmed:affiliation |
Medizinische Klinik II, Klinikum Grosshadern, Universität München.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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