Linked Life Data

2849925

Source:http://linkedlifedata.com/resource/pubmed/id/2849925

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1989-2-2
pubmed:abstractText
The induction of Epstein-Barr virus (EBV) determined antigens and virus production were observed when the EBV-non producer but genome positive cell line, A2L/AH or AdL, was cocultivated with the fibroblast dominant cells, NPC-fib derived from the primary culture of nasopharyngeal tissues. Such effect was not found when the EBV-genome positive cells were treated with cell free culture medium prepared from the supernatants of cocultivation or cultured medium of NPC-fib cells. It was considered to indicate that intercellular communication influenced the reactivation of EBV genome and promoted the cells for viral productive cycle. The cytoplasmic substances of fibroblastoid cells entered to the cytoplasm of EBV-non producer but genome positive cells, passing through the cell-to-cell membrane channels mediated by intercellular communication, and some of the transferred substances might have promoted EBV production.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0385-8146
pubmed:author
pubmed:issnType
Print
pubmed:volume
15
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
137-43
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Induction effect of Epstein-Barr virus specific antigens and viral production by intercellular communication.
pubmed:affiliation
Department of Otorhinolaryngology, School of Medicine, Kanazawa University, Japan.
pubmed:publicationType
Journal Article