Linked Life Data

2845897

Source:http://linkedlifedata.com/resource/pubmed/id/2845897

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1988-11-15
pubmed:abstractText
Granulocyte adherence and superoxide anion generation were investigated in vitro in the presence of dialysis membrane fragments incubated with normal human polymorphonuclear cells. Dialysis membranes made from cellulosic material or non-cellulosic material like polyacrylonitrile, polymethylmetacrylate, and polysulfone were tested. The membrane surface area varied (1-5 cm2) while the membrane surface/polymorphonuclear cells ratio was maintained constant (2 X 10(6) cells/cm2). The contact of polymorphonuclear cells with increasing membrane surface area generated a significant decrease of superoxide anion generation (5-80% of inhibition) and produced an increase of granulocyte adherence (5-52%). This phenomenon was observed for all the tested membranes, whether opsonized zymosan or phorbol myristate acetate were used as stimuli. Similar results were obtained after washing the dialysis membrane or when polymorphonuclear cells were suspended in homologous serum. In vitro exposure of granulocytes to cellulosic or non-cellulosic dialysis membranes caused a surface-area dependent modification of polymorphonuclear functions.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0160-564X
pubmed:author
pubmed:issnType
Print
pubmed:volume
12
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
341-4
pubmed:dateRevised
2006-4-17
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Influence of the surface area of different dialysis membranes on granulocyte adherence and superoxide generation.
pubmed:affiliation
Laboratoire de Biochimie A, Hôpital Cochin, Paris, France.
pubmed:publicationType
Journal Article