Linked Life Data

2845290

Source:http://linkedlifedata.com/resource/pubmed/id/2845290

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
1988-11-21
pubmed:abstractText
Glioblastoma multiforme with "adenoid formation" (Kepes) in the temporal lobe of a 70 year old man was presented. In addition to the classical features of glioblastoma multiforme, the tumor presented a pattern of anastomosing trabeculae of polygonal cells, mimicking epithelial tubules, in a myxoid stroma. On electron microscopic examination, the tumor cells were devoid of well-developed cytoplasmic processes. The cytoplasm of some tumor cells contained glycogen particles and lipid vacuoles in addition to usual organelles. The cell surface was partly covered by basal lamina associated with half desmosomes and had occasional filopodia-like cytoplasmic projections. A few tumor cells contained a dense intracytoplasmic accumulation of glial filaments. Intercellular junctional complexes were poorly developed. There was no evidence of differentiation of tumor cells toward ependymal cells or epithelial cells. These electron microscopic findings suggest that this tumor is predominantly composed of immature astrocytes. In spite of a superficial resemblance to adenocarcinoma on light microscopy, the tumor cells are devoid of the differentiating features of epithelial neoplasms, and their ultrastructure is essentially similar to that of glioblastoma multiforme.
pubmed:language
jpn
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0301-2603
pubmed:author
pubmed:issnType
Print
pubmed:volume
16
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
997-1003
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
[Fine structure of glioblastoma multiforme with "adenoid formation"].
pubmed:affiliation
Bluestone Laboratory, Division of Neuropathology, Montefiore Medical Center, New York.
pubmed:publicationType
Journal Article, English Abstract