rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
1
|
pubmed:dateCreated |
1988-10-5
|
pubmed:abstractText |
We report the purification, structure and biological properties of a peptide of novel sequence from human granulocytes that inhibits ACTH stimulated synthesis of corticosterone in rat adrenal cell suspensions. The peptide HP-4 is homologous to a previously described human granulocyte peptide HP-1 that has no anti-ACTH activity.
|
pubmed:grant |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Aug
|
pubmed:issn |
0006-291X
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
30
|
pubmed:volume |
155
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
524-9
|
pubmed:dateRevised |
2007-11-14
|
pubmed:meshHeading |
pubmed-meshheading:2843187-Adrenal Glands,
pubmed-meshheading:2843187-Adrenocorticotropic Hormone,
pubmed-meshheading:2843187-Amino Acid Sequence,
pubmed-meshheading:2843187-Animals,
pubmed-meshheading:2843187-Cell Line,
pubmed-meshheading:2843187-Cricetinae,
pubmed-meshheading:2843187-Granulocytes,
pubmed-meshheading:2843187-Growth Inhibitors,
pubmed-meshheading:2843187-Humans,
pubmed-meshheading:2843187-Mice,
pubmed-meshheading:2843187-Molecular Sequence Data,
pubmed-meshheading:2843187-Peptides,
pubmed-meshheading:2843187-Rats,
pubmed-meshheading:2843187-Structure-Activity Relationship
|
pubmed:year |
1988
|
pubmed:articleTitle |
Structure of a novel human granulocyte peptide with anti-ACTH activity.
|
pubmed:affiliation |
Royal Victoria Hospital, Department of Medicine, Montreal, Quebec, Canada.
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|