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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1-2
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pubmed:dateCreated |
1988-10-13
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pubmed:abstractText |
DSIP and CLIP [ACTH(18-39)] immunoreactive (IR) neurons and fibers were examined in the human hypophysis and pituitary stalk using immunmohistofluorescence and peroxidase-antiperoxidase methods. Double-stained and adjacent stained sections demonstrate that DSIP is colocalized in about 75% of CLIP-IR-like cells in the anterior pituitary and in residual intermediate lobe cells. Only few CLIP-IR-like fibers are observed in the posterior lobe. On the contrary, a high density of DSIP-IR fibers is visualized in the stalk. It is suggested that DSIP acts as a sleep promoting factor (one of many other actions) and that CLIP increases the paradoxical sleep, so that these two peptides could play a role in the regulating system of the sleep-waking cycle.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Adrenocorticotropic Hormone,
http://linkedlifedata.com/resource/pubmed/chemical/Corticotropin-Like Intermediate...,
http://linkedlifedata.com/resource/pubmed/chemical/Delta Sleep-Inducing Peptide,
http://linkedlifedata.com/resource/pubmed/chemical/Peptide Fragments
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0304-3940
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
19
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pubmed:volume |
90
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
78-82
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2842706-Adrenocorticotropic Hormone,
pubmed-meshheading:2842706-Corticotropin-Like Intermediate Lobe Peptide,
pubmed-meshheading:2842706-Delta Sleep-Inducing Peptide,
pubmed-meshheading:2842706-Humans,
pubmed-meshheading:2842706-Immunohistochemistry,
pubmed-meshheading:2842706-Peptide Fragments,
pubmed-meshheading:2842706-Pituitary Gland
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pubmed:year |
1988
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pubmed:articleTitle |
Distribution and colocalization of delta sleep inducing peptide (DSIP) with corticotropin-like intermediate lobe peptide (CLIP) in the human hypophysis.
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pubmed:affiliation |
Division of Morphological Psychopathology, University, Department of Psychiatry, Geneva, Switzerland.
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pubmed:publicationType |
Journal Article
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