Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9
pubmed:dateCreated
1988-10-6
pubmed:abstractText
Serratia marcescens, a gram-negative enteric bacterium, is capable of secreting a number of proteins extracellularly. The types of activity found in the growth media include proteases, chitinases, a nuclease, and a lipase. Genetic studies have been undertaken to investigate the mechanisms used for the extracellular secretion of these exoproteins by S. marcescens. Many independent mutations affecting the extracellular enzymes were isolated after chemical and transposon mutagenesis. Using indicator media, we have identified loci involved in the production or excretion of extracellular protease, nuclease, or chitinase by S. marcescens. None of the mutations represented general extracellular-excretion mutants; in no case was the production or excretion of multiple exoproteins affected. A variety of loci were identified, including regulatory mutations affecting nuclease and chitinase expression. A number of phenotypically different protease mutants arose. Some of them may represent different gene products required for the production and excretion of the major metalloprotease, a process more complex than that for the other S. marcescens exoproteins characterized to date.
pubmed:grant
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/2842305-159458, http://linkedlifedata.com/resource/pubmed/commentcorrection/2842305-16453672, http://linkedlifedata.com/resource/pubmed/commentcorrection/2842305-230176, http://linkedlifedata.com/resource/pubmed/commentcorrection/2842305-2981795, http://linkedlifedata.com/resource/pubmed/commentcorrection/2842305-2982794, http://linkedlifedata.com/resource/pubmed/commentcorrection/2842305-3002271, http://linkedlifedata.com/resource/pubmed/commentcorrection/2842305-3011754, http://linkedlifedata.com/resource/pubmed/commentcorrection/2842305-3016665, http://linkedlifedata.com/resource/pubmed/commentcorrection/2842305-3319779, http://linkedlifedata.com/resource/pubmed/commentcorrection/2842305-348145, http://linkedlifedata.com/resource/pubmed/commentcorrection/2842305-361718, http://linkedlifedata.com/resource/pubmed/commentcorrection/2842305-371774, http://linkedlifedata.com/resource/pubmed/commentcorrection/2842305-378936, http://linkedlifedata.com/resource/pubmed/commentcorrection/2842305-383576, http://linkedlifedata.com/resource/pubmed/commentcorrection/2842305-3896116, http://linkedlifedata.com/resource/pubmed/commentcorrection/2842305-3902791, http://linkedlifedata.com/resource/pubmed/commentcorrection/2842305-3972770, http://linkedlifedata.com/resource/pubmed/commentcorrection/2842305-4894282, http://linkedlifedata.com/resource/pubmed/commentcorrection/2842305-6090392, http://linkedlifedata.com/resource/pubmed/commentcorrection/2842305-6091132, http://linkedlifedata.com/resource/pubmed/commentcorrection/2842305-6281131, http://linkedlifedata.com/resource/pubmed/commentcorrection/2842305-6295879, http://linkedlifedata.com/resource/pubmed/commentcorrection/2842305-6319969, http://linkedlifedata.com/resource/pubmed/commentcorrection/2842305-6339072, http://linkedlifedata.com/resource/pubmed/commentcorrection/2842305-6345794, http://linkedlifedata.com/resource/pubmed/commentcorrection/2842305-6374659, http://linkedlifedata.com/resource/pubmed/commentcorrection/2842305-6389513, http://linkedlifedata.com/resource/pubmed/commentcorrection/2842305-6396497, http://linkedlifedata.com/resource/pubmed/commentcorrection/2842305-6427194, http://linkedlifedata.com/resource/pubmed/commentcorrection/2842305-6833182, http://linkedlifedata.com/resource/pubmed/commentcorrection/2842305-6990888, http://linkedlifedata.com/resource/pubmed/commentcorrection/2842305-7026050, http://linkedlifedata.com/resource/pubmed/commentcorrection/2842305-7050085
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0021-9193
pubmed:author
pubmed:issnType
Print
pubmed:volume
170
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
4141-6
pubmed:dateRevised
2010-9-9
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Genetic analysis of extracellular proteins of Serratia marcescens.
pubmed:affiliation
Department of Biology, Texas A&M University, College Station 77843.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't