Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1988-9-9
|
pubmed:abstractText |
Diazepam, an antianxietic agent, antagonized the stress-induced analgesia (SIA) distinctively depending on the characteristics of the stress. Psychological (PSY, using communication box)-SIA was completely blocked by 1 or 2 mg/kg of diazepam in the tail pinch (TP) method, but not antagonized by 1 mg/kg of the drug in the tail flick test. Swimming-SIA was resistant to diazepam in both methods and footshock-SIA was only suppressed slightly by 2 mg/kg in the TP method. Thus, emotional factors play an essential role in the production of PSY-SIA, although the participation of the factors in the other SIAs can not be excluded.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
0021-5198
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
46
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
418-20
|
pubmed:dateRevised |
2003-11-14
|
pubmed:meshHeading |
pubmed-meshheading:2841518-Analgesia,
pubmed-meshheading:2841518-Animals,
pubmed-meshheading:2841518-Diazepam,
pubmed-meshheading:2841518-Electroshock,
pubmed-meshheading:2841518-Emotions,
pubmed-meshheading:2841518-Male,
pubmed-meshheading:2841518-Mice,
pubmed-meshheading:2841518-Naloxone,
pubmed-meshheading:2841518-Receptors, Opioid,
pubmed-meshheading:2841518-Stress, Psychological,
pubmed-meshheading:2841518-Swimming
|
pubmed:year |
1988
|
pubmed:articleTitle |
Distinctive implication of emotional factors in various types of stress-induced analgesia.
|
pubmed:affiliation |
Department of Pharmacology, Faculty of Pharmaceutical Sciences, Nagasaki University, Japan.
|
pubmed:publicationType |
Journal Article
|