Linked Life Data

2839974

Source:http://linkedlifedata.com/resource/pubmed/id/2839974

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1988-8-25
pubmed:abstractText
Alpha-thalassemia is very common in Thailand. Interaction of the different types of alpha-thalassemia can lead to many alpha-thalassemia syndromes. In this study the authors compare the hematologic data of subjects with various alpha-thalassemia phenotypes. Designation of the genotypes was based on family study and DNA mapping. The results show that there are equivocal hematologic findings among those who have similar molecular defects, i.e., alpha-thalassemia-2 and hemoglobin (Hb) Constant Spring heterozygotes: alpha-thalassemia 1, homozygous alpha-thalassemia 2, and alpha-thalassemia 2/Hb Constant Spring. The severity of these alpha-thalassemia syndromes correlates with the alpha-globin gene expression calculated from the finding of Liebhaber (Liebhaber SA, et al. J Biol Chem 1986; 261:15327-15333).
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0002-9173
pubmed:author
pubmed:issnType
Print
pubmed:volume
90
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
193-6
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Hematologic changes in alpha-thalassemia.
pubmed:affiliation
Thalassemia Center, Faculty of Graduate Studies, Mahidol University, Bangkok, Thailand.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't