Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1988-8-18
pubmed:abstractText
Two fiber-supplemented enteral formulas were recently introduced for patient application, Susta II and Enrich (12.4-g and 38.5-g soy polysaccharide/2000 kcal, respectively). This investigation had a 3-fold purpose: to determine if and to what extent fiber-supplementation changes the chemical composition of stool relative to a fiber-free formula (Ensure); to establish the clinical tolerance of the two new formulas; and to quantify the effects of soy polysaccharide on nutrient bioavailability. The study was conducted in two consecutive phases: A (n = 6 subjects; random assignment to either Ensure or Susta II for 1-2 weeks followed by isocaloric cross-over to the alternate formula for an equal period of time) and B (n = 8 subjects evaluated as in phase A except Enrich replaced Ensure). Each balance week consisted of clinical/subjective monitoring, evaluation of stool composition (H2O and dry weight), apparent nutrient absorption (energy, fat, N, P, K, Ca, Mg, Zn, Na, and Cl), and metabolic balance (N, P, K, Ca, Mg, Na, and Cl). Relative to the fiber-free formula the two fiber-supplemented solutions produced increases in fecal N, fat, H2O, and minerals of variable magnitude; there were corresponding reductions in net absorption of organic compounds and minerals. The additional minerals added to the fiber-supplemented formulas and the minimal effects on N absorption preserved balance; the retention of N, P, K, Ca, Mg, Na, and Cl were similar for all three formulas. No adverse clinical effects of the fiber-supplemented formulas were noted.(ABSTRACT TRUNCATED AT 250 WORDS)
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0148-6071
pubmed:author
pubmed:issnType
Print
pubmed:volume
12
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
265-73
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed-meshheading:2839724-Absorption, pubmed-meshheading:2839724-Adult, pubmed-meshheading:2839724-Aged, pubmed-meshheading:2839724-Biological Availability, pubmed-meshheading:2839724-Dietary Fats, pubmed-meshheading:2839724-Dietary Fiber, pubmed-meshheading:2839724-Digestive System, pubmed-meshheading:2839724-Electrolytes, pubmed-meshheading:2839724-Energy Intake, pubmed-meshheading:2839724-Enteral Nutrition, pubmed-meshheading:2839724-Feces, pubmed-meshheading:2839724-Female, pubmed-meshheading:2839724-Food, Formulated, pubmed-meshheading:2839724-Humans, pubmed-meshheading:2839724-Male, pubmed-meshheading:2839724-Middle Aged, pubmed-meshheading:2839724-Nitrogen, pubmed-meshheading:2839724-Nutrition Disorders, pubmed-meshheading:2839724-Phosphorus, pubmed-meshheading:2839724-Polysaccharides, pubmed-meshheading:2839724-Soybeans
pubmed:articleTitle
Fiber supplementation of enteral formulas: effects on the bioavailability of major nutrients and gastrointestinal tolerance.
pubmed:affiliation
Department of Medicine, Emory University School of Medicine, Atlanta, Georgia.
pubmed:publicationType
Journal Article, Clinical Trial, Research Support, U.S. Gov't, P.H.S., Randomized Controlled Trial, Research Support, Non-U.S. Gov't