Linked Life Data

2838938

Source:http://linkedlifedata.com/resource/pubmed/id/2838938

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1988-8-1
pubmed:abstractText
Oral administration of dimethyldithiocarbamate pesticides (ferbam, ziram or sodium dimethyldithiocarbamate) or thiram together with nickel resulted in increased levels of the metal in several tissues of rats, in comparison with animals given only nickel. In contrast, the administration of nickel together with ethylene- or propylenebisdithiocarbamates (zineb, maneb, nabam or propineb) resulted in unchanged tissue levels or, most marked for nabam, reduced the tissue concentrations of the metal. Among the compounds which were able to increase tissue levels of nickel, thiram was the most effective one, followed in decreasing order by ferbam, ziram and sodium dimethyldithiocarbamate. The central nervous system was among the tissues which showed the highest relative increase. For thiram, an accumulation of nickel was observed in the pancreatic islets. The results are discussed in relation to the formation of chelates between nickel and the studied compounds or their metabolites.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0378-4274
pubmed:author
pubmed:issnType
Print
pubmed:volume
42
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
87-98
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Effect of thiram and dithiocarbamate pesticides on the gastrointestinal absorption and distribution of nickel in mice.
pubmed:affiliation
Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, the Swedish University of Agricultural Sciences, Uppsala.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't