Linked Life Data

2838619

Source:http://linkedlifedata.com/resource/pubmed/id/2838619

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-4
pubmed:dateCreated
1988-8-8
pubmed:abstractText
Intracellular recordings were obtained from vagal neurones and their response to oxytocin was investigated in slices from the rat brainstem. Following recording, Lucifer Yellow was injected into the cells in order to verify their localization within the dorsal motor nucleus of the vagus nerve. Virtually all neurones throughout the rostro-caudal extent of the nucleus increased their rate of firing in the presence of 10-1000 nM oxytocin and their membrane depolarized in a reversible, concentration-dependent manner. This excitation was probably exerted directly on the impaled cells rather than being synaptically mediated, since it persisted in a low calcium-high magnesium medium or in the presence of tetrodotoxin. These data provide evidence for a direct membrane effect of oxytocin on a defined population of neurones in the rat brain.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0197-5110
pubmed:author
pubmed:issnType
Print
pubmed:volume
8
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
273-82
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Electrophysiological evidence for oxytocin receptors on neurones located in the dorsal motor nucleus of the vagus nerve in the rat brainstem.
pubmed:affiliation
Department of Physiology, University Medical Center, Geneva, Switzerland.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't