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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
1988-7-25
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pubmed:abstractText |
The possibility of DNA-binding proteins interacting in vitro with the polymerase II transcriptional machinery was explored by using a competition assay with individual target sequences for enhancer-binding factors. Transcription factors binding to at least five specific enhancer sequences mediate the activity of the human cytomegalovirus immediate-early 1 gene in vitro. Furthermore, our data suggest that individual DNA-bound enhancer factors can interact with the promoter transcription complex.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/2837656-2885756,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2837656-2956091,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2837656-2982105,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2837656-2985280,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2837656-2991567,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2837656-2998773,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2837656-3018583,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2837656-3031512,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2837656-3035545,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2837656-3301328,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2837656-498279,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2837656-6098465
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0270-7306
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
8
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1809-11
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:2837656-Cytomegalovirus,
pubmed-meshheading:2837656-Enhancer Elements, Genetic,
pubmed-meshheading:2837656-Genes, Viral,
pubmed-meshheading:2837656-Kinetics,
pubmed-meshheading:2837656-Plasmids,
pubmed-meshheading:2837656-RNA Polymerase II,
pubmed-meshheading:2837656-Transcription, Genetic,
pubmed-meshheading:2837656-Transcription Factors
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pubmed:year |
1988
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pubmed:articleTitle |
Multiple sequence-specific transcription factors modulate cytomegalovirus enhancer activity in vitro.
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pubmed:affiliation |
Laboratory of Biochemistry and Metabolism, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland 20892.
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pubmed:publicationType |
Journal Article
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