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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1988-7-8
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pubmed:abstractText |
The pathogenicity of Getah virus for swine was examined. All 8 pigs (4 adults and 4 piglets) inoculated with Strains MIP-99 and MI-110 developed pyrexia ranging from 39.4 to 40.7 degrees C and anorexia. Mild depression and diarrhea were observed in 2 of the 4 piglets. These clinical signs were transient. Viremia occurred 1-2 days post-inoculation (p.i.) and the maximum titer was 10(3.0) TCID50 0.1 ml-1. The virus was recovered from a piglet autopsied on Day 3 p.i. from spleen and various lymph nodes. The maximum titer of virus (10(3.75) TCID50 0.1 g-1) was detected in the inguinal lymph node. Seroconversion was demonstrated in all the pigs on Day 6 p.i. These results suggest that Getah virus is mildly pathogenic for swine, which may play a role as an amplifying host in nature.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0378-1135
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
16
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
295-301
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:2836997-Alphavirus,
pubmed-meshheading:2836997-Animals,
pubmed-meshheading:2836997-Anorexia,
pubmed-meshheading:2836997-Antibodies, Viral,
pubmed-meshheading:2836997-Diarrhea,
pubmed-meshheading:2836997-Female,
pubmed-meshheading:2836997-Fever,
pubmed-meshheading:2836997-Lymph Nodes,
pubmed-meshheading:2836997-Male,
pubmed-meshheading:2836997-Spleen,
pubmed-meshheading:2836997-Swine,
pubmed-meshheading:2836997-Swine Diseases,
pubmed-meshheading:2836997-Togaviridae Infections,
pubmed-meshheading:2836997-Viremia
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pubmed:year |
1988
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pubmed:articleTitle |
Clinical and virological observations on swine experimentally infected with Getah virus.
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pubmed:affiliation |
Equine Research Institute, Japan Racing Association, Tochigi.
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pubmed:publicationType |
Journal Article
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