Linked Life Data

2835932

Source:http://linkedlifedata.com/resource/pubmed/id/2835932

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-6
pubmed:dateCreated
1988-6-23
pubmed:abstractText
We analyzed the prognostic significance of tumor histology, location, treatment, and selected clinical features at presentation in 91 consecutive patients with malignant gliomas diagnosed by stereotactic biopsy. In 64 patients with glioblastoma multiforme (GBM) the following factors were associated with longer survival: lobar tumor location, adequate radiation therapy (RT) tumor dose 5,000-6,000 cGy, Karnofsky performance rating (KPR) at presentation greater than or equal to 70, and a normal level of consciousness before biopsy. In 27 patients with anaplastic astrocytoma, factors associated with longer survival were lobar tumor location, adequate RT, age less than 40 years at presentation, and a history of seizures. Delayed cytoreductive surgery in lobar GBM extended median survival but did not improve long-term survival. For patients with deep or midline malignant gliomas and for selected patients with lobar tumors, stereotactic biopsy followed by RT may be the most reasonable initial treatment strategy.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0302-2773
pubmed:author
pubmed:issnType
Print
pubmed:volume
50
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
183-7
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1987
pubmed:articleTitle
Factors determining survival of patients with malignant gliomas diagnosed by stereotactic biopsy.
pubmed:affiliation
Department of Neurological Surgery, University of Pittsburgh, Pa.
pubmed:publicationType
Journal Article