|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
1
|
|
pubmed:dateCreated |
1988-5-31
|
|
pubmed:abstractText |
Triphasic oral contraceptive (Logynon) induced a significant increase (36%) in the maximal binding capacity of platelet membranes for [3H]imipramine. The increase was achieved in the second Logynon cycle as compared to pretreatment and first Logynon cycle binding values. The pill contains a combination of ethinyl estradiol and levonorgestrel, and it is as yet unclear which of the two hormones is responsible for the up-regulatory effect. The increase in the density of platelet imipramine binding sites may reflect a similar alteration in brain. The increase in imipramine binding did not correlate with alteration in mood as assessed by Beck Depression Inventory scores.
|
|
pubmed:keyword |
http://linkedlifedata.com/resource/pubmed/keyword/Asia,
http://linkedlifedata.com/resource/pubmed/keyword/Biology,
http://linkedlifedata.com/resource/pubmed/keyword/Contraception,
http://linkedlifedata.com/resource/pubmed/keyword/Contraceptive Agents,
http://linkedlifedata.com/resource/pubmed/keyword/Contraceptive Agents, Estrogen,
http://linkedlifedata.com/resource/pubmed/keyword/Contraceptive Agents, Female,
http://linkedlifedata.com/resource/pubmed/keyword/Contraceptive Agents, Progestin,
http://linkedlifedata.com/resource/pubmed/keyword/Contraceptive Methods,
http://linkedlifedata.com/resource/pubmed/keyword/Depression,
http://linkedlifedata.com/resource/pubmed/keyword/Developed Countries,
http://linkedlifedata.com/resource/pubmed/keyword/Developing Countries,
http://linkedlifedata.com/resource/pubmed/keyword/Diseases,
http://linkedlifedata.com/resource/pubmed/keyword/ETHINYL ESTRADIOL,
http://linkedlifedata.com/resource/pubmed/keyword/Endocrine System,
http://linkedlifedata.com/resource/pubmed/keyword/Family Planning,
http://linkedlifedata.com/resource/pubmed/keyword/Hormone Receptors,
http://linkedlifedata.com/resource/pubmed/keyword/Hormones,
http://linkedlifedata.com/resource/pubmed/keyword/ISRAEL,
http://linkedlifedata.com/resource/pubmed/keyword/Levonorgestrel,
http://linkedlifedata.com/resource/pubmed/keyword/MENTAL DISORDERS,
http://linkedlifedata.com/resource/pubmed/keyword/Mediterranean Countries,
http://linkedlifedata.com/resource/pubmed/keyword/Membrane Proteins,
http://linkedlifedata.com/resource/pubmed/keyword/Oral Contraceptives,
http://linkedlifedata.com/resource/pubmed/keyword/Oral Contraceptives, Combined,
http://linkedlifedata.com/resource/pubmed/keyword/Oral Contraceptives, Phasic,
http://linkedlifedata.com/resource/pubmed/keyword/Physiology,
http://linkedlifedata.com/resource/pubmed/keyword/Western Asia
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Carrier Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Contraceptives, Oral, Hormonal,
http://linkedlifedata.com/resource/pubmed/chemical/Ethinyl Estradiol,
http://linkedlifedata.com/resource/pubmed/chemical/Ethinyl Estradiol-Norgestrel...,
http://linkedlifedata.com/resource/pubmed/chemical/Imipramine,
http://linkedlifedata.com/resource/pubmed/chemical/Norgestrel,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Drug,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Neurotransmitter,
http://linkedlifedata.com/resource/pubmed/chemical/imipramine receptor
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jan
|
|
pubmed:issn |
0165-1781
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
23
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
23-9
|
|
pubmed:dateRevised |
2008-4-17
|
|
pubmed:meshHeading |
pubmed-meshheading:2834763-Adult,
pubmed-meshheading:2834763-Blood Platelets,
pubmed-meshheading:2834763-Carrier Proteins,
pubmed-meshheading:2834763-Contraceptives, Oral, Hormonal,
pubmed-meshheading:2834763-Depressive Disorder,
pubmed-meshheading:2834763-Ethinyl Estradiol,
pubmed-meshheading:2834763-Ethinyl Estradiol-Norgestrel Combination,
pubmed-meshheading:2834763-Female,
pubmed-meshheading:2834763-Humans,
pubmed-meshheading:2834763-Imipramine,
pubmed-meshheading:2834763-Norgestrel,
pubmed-meshheading:2834763-Psychological Tests,
pubmed-meshheading:2834763-Receptors, Drug,
pubmed-meshheading:2834763-Receptors, Neurotransmitter
|
|
pubmed:year |
1988
|
|
pubmed:articleTitle |
Up-regulatory effect of triphasic oral contraceptive on platelet 3H-imipramine binding sites.
|
|
pubmed:affiliation |
Geha Psychiatric Hospital, Belinson Medical Center, Tel-Aviv, Israel.
|
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't
|
