Linked Life Data

2832992

Source:http://linkedlifedata.com/resource/pubmed/id/2832992

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1988-4-28
pubmed:abstractText
The range of ultrastructural morphology was studied in 107 male germ cell neoplasm to assess relationships among tumor subtypes and to consolidate diagnostic criteria. Eighty-three pure-pattern neoplasms including 47 seminomas, 26 embryonal carcinomas, 10 endodermal sinus tumors, and 24 mixed germ cell tumors were analyzed. In the seminoma category, 4 cases showing cell surface specialization in keeping with early carcinomatous transformation were noted. The finding suggested a closer link between seminoma and nonseminomatous germ cell tumors than had been traditionally recognized and was in keeping with other clinical, histologic, biochemical, and xenograft observations. Subtypes of nonseminomatous germ cell tumors also exhibited a continuum of ultrastructural morphology with some types such as embryonal carcinoma and endodermal sinus tumor often blending together. At a practical level, electron microscopy has been of value in selected differential diagnoses such as seminoma versus lymphoma.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0191-3123
pubmed:author
pubmed:issnType
Print
pubmed:volume
12
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
67-86
pubmed:dateRevised
2009-6-26
pubmed:meshHeading
pubmed:articleTitle
The ultrastructure and histogenesis of male germ neoplasia with emphasis on seminoma with early carcinomatous features.
pubmed:affiliation
Department of Pathology, Sunnybrook Medical Centre, Toronto, Ontario, Canada.
pubmed:publicationType
Journal Article