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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1988-5-4
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pubmed:abstractText |
Muscle biopsies from a series of myotonic dystrophy patients were analysed for expression of the nerve regulated gene products neural cell adhesion molecule (N-CAM) and 5.1H11. All eight biopsy specimens tested strongly expressed N-CAM and 5.1H11 as assessed by indirect immunofluorescence analysis. These results can be compared with those of Renaud et al (Nature, 1986;319:678) that show apamin binding to be a good marker of myotonic dystrophy muscle membranes. We suggest that in myotonic dystrophy a number of nerve regulated membrane markers are precociously expressed by innervated myofibres and that these are likely to be secondary manifestations resulting from an unidentified primary defect.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/2832545-2419758,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2832545-2580309,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2832545-3016602,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2832545-3295121,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2832545-3297787,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2832545-3512581,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2832545-3891323,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2832545-3891761,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2832545-3892537,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2832545-3900817,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2832545-6188996,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2832545-6322759,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2832545-6329722,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2832545-6392332,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2832545-6620325,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2832545-6875542,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2832545-6881909,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2832545-6969855
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0022-3050
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
51
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
136-8
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:2832545-Adult,
pubmed-meshheading:2832545-Antigens, Surface,
pubmed-meshheading:2832545-Biopsy,
pubmed-meshheading:2832545-Cell Adhesion Molecules,
pubmed-meshheading:2832545-Female,
pubmed-meshheading:2832545-Fluorescent Antibody Technique,
pubmed-meshheading:2832545-Humans,
pubmed-meshheading:2832545-Male,
pubmed-meshheading:2832545-Membrane Glycoproteins,
pubmed-meshheading:2832545-Middle Aged,
pubmed-meshheading:2832545-Muscles,
pubmed-meshheading:2832545-Muscular Dystrophies,
pubmed-meshheading:2832545-Potassium Channels,
pubmed-meshheading:2832545-Receptors, Neurotransmitter
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pubmed:year |
1988
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pubmed:articleTitle |
Expression of membrane antigens in myotonic dystrophy.
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pubmed:affiliation |
Institute of Neurology, Queen Square, London, UK.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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