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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1988-4-11
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pubmed:abstractText |
Using a DNA probe for the switch region of immunoglobulin heavy chain genes, together with the restriction endonuclease Sst I, we detected a particular polymorphic DNA pattern in 17 of 28 patients (60.7%) with psoriatic arthropathy but in only 5 of 41 patients (12.2%) with psoriasis alone. Our findings suggest that genes in the immunoglobulin region confer susceptibility to the development of arthropathy in patients with psoriasis.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0004-3591
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
31
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
276-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2831908-Adult,
pubmed-meshheading:2831908-Arthritis,
pubmed-meshheading:2831908-DNA,
pubmed-meshheading:2831908-Endonucleases,
pubmed-meshheading:2831908-Humans,
pubmed-meshheading:2831908-Immunoglobulin Heavy Chains,
pubmed-meshheading:2831908-Middle Aged,
pubmed-meshheading:2831908-Nucleic Acid Hybridization,
pubmed-meshheading:2831908-Polymorphism, Genetic,
pubmed-meshheading:2831908-Psoriasis
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pubmed:year |
1988
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pubmed:articleTitle |
Arthritis in patients with psoriasis is associated with an immunoglobulin gene polymorphism.
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pubmed:affiliation |
Rheumatology Unit, United Medical School, Guy's Hospital, London, UK.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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