Linked Life Data

2830663

Source:http://linkedlifedata.com/resource/pubmed/id/2830663

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1988-3-31
pubmed:abstractText
Sensory-processing dysfunctions, deficit states, and the combinations of seemingly disparate behavioral symptoms of schizophrenia are addressed with regard to a common thread--the possibility of dysfunctional processing in the thalamus. Recent views of the connectional neuroanatomy and electrical activity of thalamus are examined. A hypothesis is presented in which disturbances in the timing and phasic neuronal activity of the thalamus and, especially, its connections with other brain regions may result in many of the behavioral manifestations of schizophrenia. It is suggested that neurotransmitter or other chemical imbalances might produce such thalamic disturbances. Experimental findings of enhanced dopamine content in the thalami of schizophrenic patients are reported. Several varieties of distributional patterns of this elevated dopamine are shown and evaluated.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0586-7614
pubmed:author
pubmed:issnType
Print
pubmed:volume
13
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
589-604
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1987
pubmed:articleTitle
Elevated thalamic dopamine: possible link to sensory dysfunctions in schizophrenia.
pubmed:affiliation
Department of Chemistry, University of Kansas, Lawrence 66045.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't