Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
1988-4-1
pubmed:abstractText
Thirty patients with different dermatologic and venereal symptoms apparently indicating herpes were examined for the presence of viruses. Two different procedures were compared: electron-microscopic analysis of negatively stained material and light-microscopic analysis of direct smears using fluorescence-labelled monoclonal mouse antibodies against herpesvirus type 1 and type 2. In 12 of the patients herpesvirus was demonstrated by at least one of the two methods: in 9 patients the specimens were positive with both methods; in 2 patients only light microscopy yielded evidence of virus material; in 1 case virus material was revealed only by electron microscopy. If electron-microscopic analysis of negatively stained clinical material is considered the standard method, the fluorescence test had a sensitivity and specificity of 90%. Thus, in the near future the latter technique may supersede the highly laborious electron-microscope method of investigation.
pubmed:language
ger
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0017-8470
pubmed:author
pubmed:issnType
Print
pubmed:volume
38
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
723-6
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1987
pubmed:articleTitle
[Comparative evaluation of herpes virus detection using fluorescence-labeled monoclonal antibodies and electron microscopy negative contrast technic in dermatovenereologic diseases. Results of a pilot study of 30 patients].
pubmed:affiliation
Dermatologische Klinik und Poliklinik der Ludwig-Maximilians-Universität München.
pubmed:publicationType
Journal Article, Comparative Study, English Abstract