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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
12
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pubmed:dateCreated |
1988-4-1
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pubmed:abstractText |
Thirty patients with different dermatologic and venereal symptoms apparently indicating herpes were examined for the presence of viruses. Two different procedures were compared: electron-microscopic analysis of negatively stained material and light-microscopic analysis of direct smears using fluorescence-labelled monoclonal mouse antibodies against herpesvirus type 1 and type 2. In 12 of the patients herpesvirus was demonstrated by at least one of the two methods: in 9 patients the specimens were positive with both methods; in 2 patients only light microscopy yielded evidence of virus material; in 1 case virus material was revealed only by electron microscopy. If electron-microscopic analysis of negatively stained clinical material is considered the standard method, the fluorescence test had a sensitivity and specificity of 90%. Thus, in the near future the latter technique may supersede the highly laborious electron-microscope method of investigation.
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pubmed:language |
ger
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Dec
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pubmed:issn |
0017-8470
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
38
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
723-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2830205-Antibodies, Monoclonal,
pubmed-meshheading:2830205-Fluorescent Antibody Technique,
pubmed-meshheading:2830205-Herpes Genitalis,
pubmed-meshheading:2830205-Humans,
pubmed-meshheading:2830205-Microscopy, Electron,
pubmed-meshheading:2830205-Microscopy, Fluorescence,
pubmed-meshheading:2830205-Pilot Projects,
pubmed-meshheading:2830205-Simplexvirus,
pubmed-meshheading:2830205-Skin
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pubmed:year |
1987
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pubmed:articleTitle |
[Comparative evaluation of herpes virus detection using fluorescence-labeled monoclonal antibodies and electron microscopy negative contrast technic in dermatovenereologic diseases. Results of a pilot study of 30 patients].
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pubmed:affiliation |
Dermatologische Klinik und Poliklinik der Ludwig-Maximilians-Universität München.
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pubmed:publicationType |
Journal Article,
Comparative Study,
English Abstract
|