Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
|
| pubmed:dateCreated |
1988-3-11
|
| pubmed:abstractText |
We describe here the transduction of murine hematopoietic progenitor cells with the dominant selectable neomycin drug-resistance (Neo) gene using a recombinant adeno-associated virus (AAV) vector. Successful transformation of progenitor cells to drug resistance was determined to be approximately 1.5% by colony formation in the presence of geneticin sulfate (G-418). The value of AAV as an alternative to the retrovirus vector systems is discussed.
|
| pubmed:grant | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Feb
|
| pubmed:issn |
0042-6822
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
162
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
483-6
|
| pubmed:dateRevised |
2007-11-14
|
| pubmed:meshHeading |
pubmed-meshheading:2829430-Bone Marrow,
pubmed-meshheading:2829430-Bone Marrow Cells,
pubmed-meshheading:2829430-Cells, Cultured,
pubmed-meshheading:2829430-Dependovirus,
pubmed-meshheading:2829430-Genetic Vectors,
pubmed-meshheading:2829430-Hematopoietic Stem Cells,
pubmed-meshheading:2829430-Humans,
pubmed-meshheading:2829430-Transformation, Genetic
|
| pubmed:year |
1988
|
| pubmed:articleTitle |
Gene transfer into hematopoietic progenitor cells mediated by an adeno-associated virus vector.
|
| pubmed:affiliation |
Department of Pathology, University of Florida, Gainesville 32610.
|
| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
|