| pubmed-article:2829374 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2829374 | lifeskim:mentions | umls-concept:C0021270 | lld:lifeskim |
| pubmed-article:2829374 | lifeskim:mentions | umls-concept:C0458827 | lld:lifeskim |
| pubmed-article:2829374 | lifeskim:mentions | umls-concept:C0034785 | lld:lifeskim |
| pubmed-article:2829374 | lifeskim:mentions | umls-concept:C0043144 | lld:lifeskim |
| pubmed-article:2829374 | lifeskim:mentions | umls-concept:C0205245 | lld:lifeskim |
| pubmed-article:2829374 | lifeskim:mentions | umls-concept:C0332120 | lld:lifeskim |
| pubmed-article:2829374 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:2829374 | pubmed:dateCreated | 1988-3-4 | lld:pubmed |
| pubmed-article:2829374 | pubmed:abstractText | The effect of nebulised salbutamol on the bronchial response to nebulised histamine was studied in five wheezy infants aged 3-12 months. The response to doubling concentrations of up to 8 g/l of histamine was assessed by the change in the maximum flow at FRC (VmaxFRC), measured by flow-volume curves produced during forced expiration with a pressure jacket. The concentration of histamine required to provoke a 30% fall in VmaxFRC (PC30) was measured. All of the infants responded to low concentrations of histamine during control tests before and after nebulised saline (mean PC30 1.07 and 0.51 g/l). On a separate day there was a similar response to histamine before salbutamol (PC30 0.57 g/l), but after salbutamol the response was completely abolished up to the maximum concentration of histamine in all subjects (PC30 greater than 8 g/l). Thus wheezy infants have highly effective beta 2 adrenoceptors in intrathoracic airways. | lld:pubmed |
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| pubmed-article:2829374 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2829374 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2829374 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:2829374 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2829374 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:2829374 | pubmed:issn | 0040-6376 | lld:pubmed |
| pubmed-article:2829374 | pubmed:author | pubmed-author:SilvermanMM | lld:pubmed |
| pubmed-article:2829374 | pubmed:author | pubmed-author:GreenSS | lld:pubmed |
| pubmed-article:2829374 | pubmed:author | pubmed-author:PrendivilleAA | lld:pubmed |
| pubmed-article:2829374 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2829374 | pubmed:volume | 42 | lld:pubmed |
| pubmed-article:2829374 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2829374 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2829374 | pubmed:pagination | 100-4 | lld:pubmed |
| pubmed-article:2829374 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:2829374 | pubmed:year | 1987 | lld:pubmed |
| pubmed-article:2829374 | pubmed:articleTitle | Airway responsiveness in wheezy infants: evidence for functional beta adrenergic receptors. | lld:pubmed |
| pubmed-article:2829374 | pubmed:affiliation | Department of Paediatrics and Neonatal Medicine, Royal Postgraduate Medical School, Hammersmith Hospital, London. | lld:pubmed |
| pubmed-article:2829374 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2829374 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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