rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
1988-3-2
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pubmed:abstractText |
Serologic reactivity against EBV-infected lines was assayed in patients with AIDS (n = 4) or the AIDS related complex (AIDS-RC) (n = 46) residing in Argentina. Anti-VCA serology was comparable to that of controls. However sera from AIDS and AIDS-RC could induce antibody dependent cell mediated cytotoxicity (ADCC) to EBV-infected cell lines (P3HRIK and Raji). ADCC activity could be recovered in the high molecular weight fractions of AIDS and AIDS-RC sera. ADCC was observed in sera with high levels of PEG precipitable material (PEG-pp) but was unrelated to the presence of complement-fixing immune complexes (Clq-F) or to anti-VCA titers. Fc receptor (FcR) bridging between target cells FcR and effector cells FcR may play a role in the outcome of total ADCC.
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pubmed:language |
spa
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pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Viral,
http://linkedlifedata.com/resource/pubmed/chemical/Antigen-Antibody Complex,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, Viral,
http://linkedlifedata.com/resource/pubmed/chemical/Capsid Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Complement Activating Enzymes,
http://linkedlifedata.com/resource/pubmed/chemical/Complement C1,
http://linkedlifedata.com/resource/pubmed/chemical/Complement C1q,
http://linkedlifedata.com/resource/pubmed/chemical/Epstein-Barr viral capsid antigen,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Fc
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pubmed:status |
MEDLINE
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pubmed:issn |
0325-7541
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pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
17
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
137-43
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2829276-AIDS-Related Complex,
pubmed-meshheading:2829276-Acquired Immunodeficiency Syndrome,
pubmed-meshheading:2829276-Antibodies, Viral,
pubmed-meshheading:2829276-Antibody-Dependent Cell Cytotoxicity,
pubmed-meshheading:2829276-Antigen-Antibody Complex,
pubmed-meshheading:2829276-Antigens, Viral,
pubmed-meshheading:2829276-Burkitt Lymphoma,
pubmed-meshheading:2829276-Capsid Proteins,
pubmed-meshheading:2829276-Cell Line,
pubmed-meshheading:2829276-Complement Activating Enzymes,
pubmed-meshheading:2829276-Complement C1,
pubmed-meshheading:2829276-Complement C1q,
pubmed-meshheading:2829276-Herpesvirus 4, Human,
pubmed-meshheading:2829276-Humans,
pubmed-meshheading:2829276-Male,
pubmed-meshheading:2829276-Receptors, Fc,
pubmed-meshheading:2829276-Tumor Cells, Cultured
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pubmed:year |
1985
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pubmed:articleTitle |
[Cytotoxicity induced by the serum of patients with AIDS and at high risk of AIDS against cells infected with Epstein-Barr virus].
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pubmed:affiliation |
Instituto de Investigaciones Hematológicas, Academia Nacional de Medicina, Buenos Aires, Argentina.
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pubmed:publicationType |
Journal Article,
English Abstract,
Research Support, Non-U.S. Gov't
|