Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2-3
pubmed:dateCreated
1988-3-18
pubmed:abstractText
A method is described for the serotyping of rotaviruses directly from samples of faeces. Serotype-specific monoclonal antibodies were used in a solid phase enzyme-immunoassay utilising a novel substrate system based on the de-phosphorylation of NADP, followed by cyclic colour reaction. This method is shown to be approximately 5-10 times more specific and sensitive than assays utilising a conventional substrate for alkaline phosphatase, and allowed serotypes to be ascribed to samples which could not be typed by other methods. The value of this method for rotavirus epidemiology and vaccine trials is discussed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0166-0934
pubmed:author
pubmed:issnType
Print
pubmed:volume
18
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
77-85
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1987
pubmed:articleTitle
Serotyping of rotavirus by NADP-enhanced enzyme-immunoassay.
pubmed:affiliation
Regional Virus Laboratory, East Birmingham Hospital, U.K.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't