rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
3
|
pubmed:dateCreated |
1988-3-21
|
pubmed:abstractText |
Rat liver S-adenosyl-L-methionine synthetase exists in two forms which are, respectively, a dimer and a tetramer of an Mr 48,500 subunit. The high-molecular-mass form is converted into the low-molecular-mass form by incubation with 1.4 M LiBr. The kinetic properties of the low-molecular-mass form obtained by LiBr treatment are the same as those obtained with the low-molecular-mass S-adenosyl-L-methionine synthetase form purified from rat liver cytosol. These results demonstrate that the differences in specific activity and regulatory properties of the high-molecular-mass and the low-molecular-mass S-adenosyl-L-methionine synthetase forms are due to their different polymeric states.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Feb
|
pubmed:issn |
0006-3002
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
10
|
pubmed:volume |
952
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
277-81
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:2827780-Animals,
pubmed-meshheading:2827780-Biopolymers,
pubmed-meshheading:2827780-Bromides,
pubmed-meshheading:2827780-Cytosol,
pubmed-meshheading:2827780-Dimethyl Sulfoxide,
pubmed-meshheading:2827780-Diphosphates,
pubmed-meshheading:2827780-Lithium,
pubmed-meshheading:2827780-Lithium Compounds,
pubmed-meshheading:2827780-Liver,
pubmed-meshheading:2827780-Methionine Adenosyltransferase,
pubmed-meshheading:2827780-Molecular Weight,
pubmed-meshheading:2827780-Rats,
pubmed-meshheading:2827780-Transferases
|
pubmed:year |
1988
|
pubmed:articleTitle |
Conversion of rat liver S-adenosyl-L-methionine synthetase from high-Mr form to low-Mr form by LiBr.
|
pubmed:affiliation |
Metabolismo, Nutrición y Hormonas, Fundación Jimenez Diaz, Madrid, Spain.
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|