Linked Life Data

2827474

Source:http://linkedlifedata.com/resource/pubmed/id/2827474

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1988-2-2
pubmed:abstractText
Desmoid tumors occur at a much higher frequency in association with familial adenomatous polyposis than with any other disease. However, published estimates of risk have varied widely. In this study we have examined the occurrence of desmoids in a population of polyposis patients in order to determine an accurate estimate of the risk of desmoid disease. The crude frequency of desmoids in our population was about 6%, but the risk was dependent on the age and sex of the individuals at risk. The lifetime risk of incurring a desmoid was 8% for males and 13% for females. The distribution of occurrence of desmoid disease with regard to age was unimodal in each sex in contrast to the multimodal distribution observed for desmoids in nonpolyposis patients. Females were more likely to be affected than males and at an earlier age. We also detected heterogeneity of risk between families segregating for the polyposis gene, with the desmoid disease tending to cluster in some of those families. Consequently crude estimates of risk should be used with caution.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0148-7299
pubmed:author
pubmed:issnType
Print
pubmed:volume
28
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
385-92
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1987
pubmed:articleTitle
Occurrence of desmoids in patients with familial adenomatous polyposis of the colon.
pubmed:affiliation
Cornell University Medical College, New York.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.