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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1979-3-29
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pubmed:abstractText |
Qualitative platelet parameters (volume, 5 hydroxy-tryptamine (5 HT) organelles studied by the mepacrine test, and density) were evaluated in 31 patients with acute leukaemia: 11 myelomonocytic (AML), 8 lymphoblastic (ALL), 12 granulocytic (AGL). Macrothrombocytosis was observed in most of the cases of AML, was rare in AGL and was never found in ALL. The 5 HT organelles/volume ratio was normal in AGL and ALL but was significantly decreased in AML. In contrast, platelet density distribution was always abnormal whatever the platelet volume and 5 HT organelle concentration. Thus, using simple new methods, convenient even in cases of thrombocytopenia, we demonstrate that qualitative platelet abnormalities are a constant feature in acue leukaemia and that they are more severe in AML.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0036-553X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
21
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
421-6
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:282662-Blood Cell Count,
pubmed-meshheading:282662-Blood Platelets,
pubmed-meshheading:282662-Cytoplasmic Granules,
pubmed-meshheading:282662-Humans,
pubmed-meshheading:282662-Leukemia,
pubmed-meshheading:282662-Leukemia, Lymphoid,
pubmed-meshheading:282662-Leukemia, Monocytic, Acute,
pubmed-meshheading:282662-Leukemia, Myeloid, Acute,
pubmed-meshheading:282662-Quinacrine,
pubmed-meshheading:282662-Serotonin,
pubmed-meshheading:282662-Thrombocytosis
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pubmed:year |
1978
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pubmed:articleTitle |
Platelet volume, density and 5 HT organelles (mepacrine test) in acute leukaemia.
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pubmed:publicationType |
Journal Article
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