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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1-2
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pubmed:dateCreated |
1988-1-26
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pubmed:abstractText |
Cardiodilatins/atrial natriuretic peptides (CDD/ANP) exhibit a common amino acid sequence: Arg101-Arg102-Ser103-Ser104. Cyclic AMP-dependent phosphorylation of Ser104 of atrial peptides with [gamma-32P]ATP enables rapid identification of cardiac hormones. The biological activity of in vitro phosphorylated cardiodilatin (CDD-28/alpha-hANP) is dramatically altered compared to the unphosphorylated peptide: the vaso-relaxant effect of cardiodilatin 28 is inhibited upon phosphorylation.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0014-5793
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
10
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pubmed:volume |
225
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
251-4
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:2826242-Animals,
pubmed-meshheading:2826242-Atrial Natriuretic Factor,
pubmed-meshheading:2826242-Cyclic AMP,
pubmed-meshheading:2826242-Muscle, Smooth, Vascular,
pubmed-meshheading:2826242-Muscle Contraction,
pubmed-meshheading:2826242-Muscle Proteins,
pubmed-meshheading:2826242-Muscle Relaxation,
pubmed-meshheading:2826242-Peptide Fragments,
pubmed-meshheading:2826242-Phosphorylation,
pubmed-meshheading:2826242-Protein Kinases,
pubmed-meshheading:2826242-Rabbits
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pubmed:year |
1987
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pubmed:articleTitle |
Relaxation of smooth muscle by cardiodilatin/atrial natriuretic peptide is inhibited by cAMP-dependent phosphorylation.
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pubmed:affiliation |
Institute of Anatomy III, University of Heidelberg, FRG.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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