Linked Life Data

2826122

Source:http://linkedlifedata.com/resource/pubmed/id/2826122

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1988-2-8
pubmed:abstractText
Asbestos fibers in vitro produce lipid peroxidation in rat lung microsomes. Butylated hydroxytoluene prevented this peroxidation. Ascorbate in low concentrations enhanced peroxidation of lipids but inhibited it at concentrations above 4 mmole/liter so that it partially protected membrane lipids from peroxidation produced by asbestos fibers. Reduced glutathione added to microsomes gave increased peroxidation at increased concentrations up to 20 mmol/liter. At 40 mmol/liter peroxidation was prevented. Glutathione had no obvious effect on the level of peroxidation produced by asbestos fibers. The 105,000g supernatant cell fraction added either with or without glutathione gave a decrease in the amount of lipid peroxidation produced by asbestos fibers. The protective action of these reducing agents suggests a possible use as prophylactic agents against the harmful effects of inhaled asbestos.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0013-9351
pubmed:author
pubmed:issnType
Print
pubmed:volume
44
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
254-9
pubmed:dateRevised
2006-10-30
pubmed:meshHeading
pubmed:year
1987
pubmed:articleTitle
Crocidolite-induced lipid peroxidation. II. Role of antioxidants.
pubmed:affiliation
National Centre for Occupational Health, Johannesburg, South Africa.
pubmed:publicationType
Journal Article