|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
1-2
|
|
pubmed:dateCreated |
1988-2-10
|
|
pubmed:abstractText |
Sertraline, a potent and selective inhibitor of serotonin uptake, was chronically administered to laboratory rats. Using in vitro receptor autoradiographic techniques, we found that the binding of [3H]dihydroalprenolol ([3H]DHA) was reduced in cortex layers IV-VI. Results of a saturation experiment indicated that the reduction in cortex layer IV was due to a change in number but not affinity of beta-adrenergic receptors.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Sep
|
|
pubmed:issn |
0006-8993
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:day |
22
|
|
pubmed:volume |
421
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
377-81
|
|
pubmed:dateRevised |
2006-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:2825912-1-Naphthylamine,
pubmed-meshheading:2825912-Animals,
pubmed-meshheading:2825912-Autoradiography,
pubmed-meshheading:2825912-Dihydroalprenolol,
pubmed-meshheading:2825912-Frontal Lobe,
pubmed-meshheading:2825912-Male,
pubmed-meshheading:2825912-Naphthalenes,
pubmed-meshheading:2825912-Parietal Lobe,
pubmed-meshheading:2825912-Rats,
pubmed-meshheading:2825912-Rats, Inbred Strains,
pubmed-meshheading:2825912-Receptors, Adrenergic, beta,
pubmed-meshheading:2825912-Serotonin,
pubmed-meshheading:2825912-Sertraline
|
|
pubmed:year |
1987
|
|
pubmed:articleTitle |
Chronic administration of sertraline, a selective serotonin uptake inhibitor, decreased the density of beta-adrenergic receptors in rat frontoparietal cortex.
|
|
pubmed:affiliation |
Department of Psychiatry, University of Utah Medical Center, Salt Lake City 84132.
|
|
pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, Non-U.S. Gov't
|
