rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
3
|
pubmed:dateCreated |
1987-12-22
|
pubmed:abstractText |
Twenty-eight days of neuroleptic treatment of 11 schizophrenics aged 16-23 years did not affect the binding values of 3H-PK 11195 to platelets. This lack of effect was in contrast to reduced peripheral benzodiazepine binding sites (PBS) observed in platelets of schizophrenics medicated over 2 years. These results may indicate that neuroleptic-induced down-regulation of PBS is a time-dependent phenomenon.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:issn |
0302-282X
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
17
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
121-3
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:2825067-Adolescent,
pubmed-meshheading:2825067-Adult,
pubmed-meshheading:2825067-Blood Platelets,
pubmed-meshheading:2825067-Female,
pubmed-meshheading:2825067-Haloperidol,
pubmed-meshheading:2825067-Humans,
pubmed-meshheading:2825067-Isoquinolines,
pubmed-meshheading:2825067-Male,
pubmed-meshheading:2825067-Psychiatric Status Rating Scales,
pubmed-meshheading:2825067-Receptors, GABA-A,
pubmed-meshheading:2825067-Schizophrenia,
pubmed-meshheading:2825067-Schizophrenic Psychology,
pubmed-meshheading:2825067-Trifluoperazine
|
pubmed:year |
1987
|
pubmed:articleTitle |
Lack of effect of 28 days of neuroleptic treatment on platelet benzodiazepine binding sites in schizophrenics.
|
pubmed:affiliation |
Department of Pharmacology, Faculty of Medicine, Technion-Israel Institute of Technology, Haifa.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|