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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
12
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pubmed:dateCreated |
1987-12-21
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pubmed:abstractText |
Bovine herpesvirus 1 has been reported to contain a thymidine kinase (tk) gene which is nonessential for virus replication. We have isolated a thymidine kinase-negative mutant of the virus and localized the mutation by marker rescue experiments to a 1.1-kilobase BglII-SalI fragment which maps at 0.47 to 0.48 on the bovine herpesvirus 1 genomic map. A thymidine kinase-negative bovine cell line isolated in our laboratory was used in these studies.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/2824831-201597,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2824831-3004022,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2824831-3018124,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2824831-3021976,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2824831-3023190,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2824831-4457349,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2824831-5902315,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2824831-6292348,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2824831-6305015,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2824831-6306279,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2824831-6316635,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2824831-6826696,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2824831-7080438,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2824831-7343541
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0022-538X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
61
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
4023-5
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:2824831-Animals,
pubmed-meshheading:2824831-Cattle,
pubmed-meshheading:2824831-Cell Line,
pubmed-meshheading:2824831-Cloning, Molecular,
pubmed-meshheading:2824831-DNA, Viral,
pubmed-meshheading:2824831-DNA Restriction Enzymes,
pubmed-meshheading:2824831-Deoxyribonuclease HindIII,
pubmed-meshheading:2824831-Genes, Viral,
pubmed-meshheading:2824831-Genetic Markers,
pubmed-meshheading:2824831-Herpesvirus 1, Bovine,
pubmed-meshheading:2824831-Mutation,
pubmed-meshheading:2824831-Phenotype,
pubmed-meshheading:2824831-Thymidine Kinase
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pubmed:year |
1987
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pubmed:articleTitle |
Map location of the thymidine kinase gene of bovine herpesvirus 1.
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pubmed:affiliation |
Laboratory of Microbiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia 19104-6049.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't
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