Linked Life Data

2824423

Source:http://linkedlifedata.com/resource/pubmed/id/2824423

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1988-1-14
pubmed:abstractText
The sensitivity of Escherichia coli to the lytic action of polymyxin B was assessed for cells grown in a chemostat at a variety of specific growth rates and under conditions of carbon, nitrogen, phosphorus and magnesium limitation. Magnesium and phosphorus limited cells demonstrated a trend of increased resistance with increasing growth-rate, whereas carbon and nitrogen limited cells increased their sensitivity as the growth rate increased. Divergent patterns of sensitivity, such as these, allowed a number of models for resistance towards polymyxin to be assessed. It was not possible to attribute polymyxin sensitivity to any single envelope component; rather the patterns of sensitivity reflect, in a complex manner, presence of envelope proteins and acidic phospholipids.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0305-7453
pubmed:author
pubmed:issnType
Print
pubmed:volume
20
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
303-12
pubmed:dateRevised
2005-11-17
pubmed:meshHeading
pubmed:year
1987
pubmed:articleTitle
Influence of specific growth rate and nutrient-limitation upon the sensitivity of Escherichia coli towards polymyxin B.
pubmed:affiliation
Department of Pharmacy, University of Manchester, UK.
pubmed:publicationType
Journal Article