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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1989-12-8
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pubmed:abstractText |
The aim of this study was to evaluate the antitumor effect and toxicity of a single course of Peptichemio at high dose (450 mg/sq m) given to children with neuroblastoma resistant to first line treatment or at relapse. A total of 28 children were treated. Seven children showed partial response, 4 minor response, 8 had stable disease, and in 8 the tumor progressed. The principal toxic effect was myelosuppression. Hemorrhagic enteritis with liver failure and toxic death occurred in 1 patient. High dose Peptichemio can be administered with tolerable toxicity, inducing tumor regression in one third of previously treated patients.
|
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0250-7005
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
9
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1157-60
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2817797-Adolescent,
pubmed-meshheading:2817797-Antineoplastic Agents,
pubmed-meshheading:2817797-Blood Cell Count,
pubmed-meshheading:2817797-Child,
pubmed-meshheading:2817797-Child, Preschool,
pubmed-meshheading:2817797-Drug Resistance,
pubmed-meshheading:2817797-Female,
pubmed-meshheading:2817797-Humans,
pubmed-meshheading:2817797-Infant,
pubmed-meshheading:2817797-Male,
pubmed-meshheading:2817797-Melphalan,
pubmed-meshheading:2817797-Neoplasm Recurrence, Local,
pubmed-meshheading:2817797-Neuroblastoma,
pubmed-meshheading:2817797-Peptichemio
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pubmed:articleTitle |
High dose peptichemio in pretreated neuroblastoma.
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pubmed:affiliation |
Giannina Gaslini Children's Hospital, Genova, Italy.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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