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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
1989-12-5
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pubmed:abstractText |
Forty-eight girls with Turner's syndrome were assigned to one of three treatments; recombinant human growth hormone (rhGH) alone, rhGH plus oxandrolone, and rhGH plus ethinyloestradiol. Treatment with rhGH alone or in combination with oxandrolone induced catch-up growth. Older girls treated with rhGH plus ethinyloestradiol showed less marked improvement. The gain in height was associated with a gain in bone diameter and cortical thickness (reflecting increased bone mass). There was a rapid loss of subcutaneous fat. These effects of growth hormone are similar to those observed in patients with growth hormone deficiency.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0300-8843
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
356
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
87-91; discussion 92
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pubmed:dateRevised |
2008-2-20
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pubmed:meshHeading |
pubmed-meshheading:2816362-Adolescent,
pubmed-meshheading:2816362-Bone Development,
pubmed-meshheading:2816362-Child,
pubmed-meshheading:2816362-Child, Preschool,
pubmed-meshheading:2816362-Drug Therapy, Combination,
pubmed-meshheading:2816362-Ethinyl Estradiol,
pubmed-meshheading:2816362-Female,
pubmed-meshheading:2816362-Growth Disorders,
pubmed-meshheading:2816362-Growth Hormone,
pubmed-meshheading:2816362-Humans,
pubmed-meshheading:2816362-Oxandrolone,
pubmed-meshheading:2816362-Recombinant Proteins,
pubmed-meshheading:2816362-Skinfold Thickness,
pubmed-meshheading:2816362-Turner Syndrome
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pubmed:year |
1989
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pubmed:articleTitle |
Effect of recombinant human growth hormone therapy on bone and clinical parameters in girls with Turner's syndrome. The Spanish Collaborative Group.
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pubmed:affiliation |
Endocrine Unit, Children's Hospital, Zaragoza, Spain.
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pubmed:publicationType |
Journal Article
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