Linked Life Data

2813988

Source:http://linkedlifedata.com/resource/pubmed/id/2813988

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1989-12-14
pubmed:abstractText
Capillary blood flow variables were measured in cremaster muscles of anesthetized Golden hamsters after isovolemic hemodilution with donor hamster plasma to mean systemic hematocrits of 49% of normal (Group 1) and 32% of normal (Group 2). Despite their different systemic hematocrits, Groups 1 and 2 showed no significant differences in any measured capillary variable. Capillary cell content decreased significantly after hemodilution from 9.4 +/- 0.8 (SE) in controls to 5.8 +/- 0.7 (Group 1) and 5.0 +/- 0.5 cells/100 microns (Group 2). Hemodilution did not change resting capillary cell velocity or capillary cell flux. Velocities were 115 +/- 14, 186 +/- 25 and 203 +/- 23 microns/sec in controls. Group 1 and Group 2, respectively, while the corresponding mean values for cell flux were 9.8 +/- 2.0, 11.5 +/- 2.1 and 11.9 +/- 2.4 cells/sec. Functional capillary density was unchanged after hemodilution, but tissue cell capacity (estimated from cell content and capillary density) attained only 50% of the expected value, being 26% (Group 1) and 16% (Group 2) of control. Thus, none of the changes in indices of capillary cell flow, capillary cell content or tissue cell capacity were directly proportional to the changes in systemic hematocrit. This suggests that tissue oxygen delivery from capillaries cannot be predicted from measured changes in systemic oxygen transport capacity.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0034-5687
pubmed:author
pubmed:issnType
Print
pubmed:volume
78
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
7-17
pubmed:dateRevised
2009-11-11
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
Microcirculation in striated muscle after acute reduction in systemic hematocrit.
pubmed:affiliation
Department of Biophysics, University of Rochester School of Medicine and Dentistry, NY 14642.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.