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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7
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pubmed:dateCreated |
1989-11-27
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pubmed:abstractText |
10 Ergostan-3-on derivatives presumably in the majority ergosta-1,4-dien-3-on derivatives could be isolated from Petunia hybrida VILM. Two were identified as the known compounds petuniasterone A and petuniasterone-C-22-O-acetate. The structures of two other compounds named petuniasterone-D-diacetate and 30-hydroxypetuniasterone A could be elucidated. The molecular formulas of the remaining substances were ascertained by mass spectroscopy. The petuniasterones inhibited the proliferation of stimulated human lymphocytes in non-cytotoxic concentrations, possessing therefore possibly immunosuppressive effects. Extracts of the plant and fractions containing a synergistically effective blue fluorescing substance retarded the multiplication speed of influenza viruses; pure petuniasterones were ineffectiv under our conditions in this regard.
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pubmed:language |
ger
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0031-7144
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
44
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
484-8
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pubmed:dateRevised |
2007-1-29
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pubmed:meshHeading |
pubmed-meshheading:2813491-Antiviral Agents,
pubmed-meshheading:2813491-Cell Survival,
pubmed-meshheading:2813491-Cells, Cultured,
pubmed-meshheading:2813491-Ergosterol,
pubmed-meshheading:2813491-Humans,
pubmed-meshheading:2813491-Immunosuppressive Agents,
pubmed-meshheading:2813491-Lymphocyte Activation,
pubmed-meshheading:2813491-Lymphocytes,
pubmed-meshheading:2813491-Mass Spectrometry,
pubmed-meshheading:2813491-Plants, Medicinal
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pubmed:year |
1989
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pubmed:articleTitle |
[Immunosuppressive and virostatic actions of sterones from Petunia hybrida Vilm].
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pubmed:affiliation |
Sektion Pharmazie, Ernst-Moritz-Arndt-Universität Greifswald.
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pubmed:publicationType |
Journal Article,
In Vitro,
English Abstract
|