Linked Life Data

2808213

Source:http://linkedlifedata.com/resource/pubmed/id/2808213

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1989-12-19
pubmed:abstractText
The proconvulsive tendency of the novel carbapenem, meropenem was compared to that of imipenem, alone and in combination with cilastatin. The potentiation of metrazole-induced convulsions in mice was measured. Both imipenem and imipenem/cilastatin caused significant potentiation of metrazole-induced convulsions at a dose of 200 mg/kg, i.v. In contrast, meropenem (50-400 mg/kg, iv) failed to exhibit any significant potentiation of metrazole-induced seizures.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0305-7453
pubmed:author
pubmed:issnType
Print
pubmed:volume
24 Suppl A
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
307-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
Meropenem: evidence of lack of proconvulsive tendency in mice.
pubmed:affiliation
ICI Pharmaceuticals Group, ICI Americas Inc., Wilmington, DE 19897.
pubmed:publicationType
Journal Article, Comparative Study