Linked Life Data

2806384

Source:http://linkedlifedata.com/resource/pubmed/id/2806384

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2-3
pubmed:dateCreated
1989-12-20
pubmed:abstractText
Based on a vasoconstrictor role for serotonin (5-HT) in various types of cardiopulmonary conditions the effect of the 5-HT2 receptor antagonist, ketanserin, on 5-HT-induced responses in the intact, isolated rat lung was investigated. 5-HT produced biphasic responses consisting of weak vasodilator and predominant, dose-dependent constrictor components. Ketanserin showed no direct vasodilator effects but could completely antagonise the 5-HT-induced vasoconstrictor responses, suggesting that this response was 5-HT2 receptor-mediated.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0014-2999
pubmed:author
pubmed:issnType
Print
pubmed:day
10
pubmed:volume
169
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
269-73
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
The effect of ketanserin on serotonin-induced vascular responses in the isolated perfused rat lung.
pubmed:affiliation
Department of Pharmacology, School of Pharmacy, University of the Western Cape, Bellville, Cape Province, South Africa.
pubmed:publicationType
Journal Article, In Vitro, Research Support, Non-U.S. Gov't