Linked Life Data

2805358

Source:http://linkedlifedata.com/resource/pubmed/id/2805358

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1989-12-1
pubmed:abstractText
Plasminogen activator activity and plasminogen independent amidolytic activity were measured in human tears by a spectrophotometric method using human plasminogen and chromogenic peptide substrate S-2251. This assay is sensitive predominantly to urokinase-like plasminogen activator. Tears were collected with glass capillaries. The activator activity in normal tears was found to be low, 0.06 +/- 0.04 (SD) IU/ml. Elevated levels were measured in the tears of patients with various types of conjunctival and corneal disorders. The affected epithelial cells of the cornea and conjunctiva were suggested to be responsible for the elevated activity. Plasminogen independent amidolytic activity was usually very low except in cases of increased permeability of the conjunctival blood vessels. The procedure is recommended as a useful tool for the study of the pathological changes in the epithelial cells of the cornea and conjunctiva.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0009-8981
pubmed:author
pubmed:issnType
Print
pubmed:day
31
pubmed:volume
183
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
323-31
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
Plasminogen activator activity and plasminogen independent amidolytic activity in tear fluid from healthy persons and patients with anterior segment inflammation.
pubmed:affiliation
Department of Biochemistry, Medical University of Debrecen, Hungary.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't