Linked Life Data

2804683

Source:http://linkedlifedata.com/resource/pubmed/id/2804683

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1989-12-1
pubmed:abstractText
Spontaneous electrophysiological activity and excitation by capsaicin of regenerating sensory fibers has been studied using 1 to 20-week-old neuromas induced in rats by ligating and transecting the saphenous nerve. Overall, spontaneous activity occurred in 12% of fibers, and capsaicin at concentrations up to 1.0 microM excited 3.8% of all the A delta-plus C-fibers examined. There was a slight increase in the incidence of spontaneous activity, but not excitation by capsaicin, with increasing age of the neuromas. The responses to capsaicin were similar to those seen with normal saphenous nerve endings, including bursting discharges and desensitization with repeated applications. The results are considered in the context of the requirements for reexpression of normal sensory capacities on regenerating sensory nerve endings.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0006-8993
pubmed:author
pubmed:issnType
Print
pubmed:day
16
pubmed:volume
499
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
363-6
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
The excitation of cutaneous nerve endings in a neuroma by capsaicin.
pubmed:affiliation
II Physiologisches Institut, Universität Heidelberg, F.R.G.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't