Linked Life Data

2797943

Source:http://linkedlifedata.com/resource/pubmed/id/2797943

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1989-11-7
pubmed:abstractText
Medium-chain triglycerides, with a chain length of eight and 10 carbon atoms, form up to 50% of the total fat content in some preterm infant formulas. In 20 small preterm infants (birthwt: 1153 +/- 227 g; mean +/- SD) fed a special formula containing 40% MCT, a primed constant oral infusion study of 1-13C-potassium octanoate was conducted to quantify the oxidation of MCT. A plateau in 13C enrichment in breath CO2 was reached in all patients within 1-3 h. Simultaneously, substrate utilization was measured using a closed system indirect calorimeter. No significant difference was found between appropriate for gestational age (n = 8) and small for gestational age (n = 12) infants in the percentage of the administered tracer that was oxidized (44.9 +/- 9.1% versus 48.5 +/- 11.0%). In all patients, the recovery was calculated to be 47.1 +/- 10.2%, which is less than previously estimated and corresponds to a mean MCT oxidation of 1.26 +/- 0.27 g/kg/d. With indirect calorimetry, a total fat oxidation of 1.42 +/- 0.84 g/kg/d in appropriate for gestational age and 2.00 +/- 0.85 g/kg/d in small for gestational age infants was found, indicating that MCT accounted for around 85% of the total fat oxidation in appropriate for gestational age versus 65% in small for gestational age infants.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0031-3998
pubmed:author
pubmed:issnType
Print
pubmed:volume
26
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
294-7
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
Quantitation of oxidation of medium-chain triglycerides in preterm infants.
pubmed:affiliation
Department of Paediatrics, Erasmus University, Rotterdam, The Netherlands.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't