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PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
16
pubmed:dateCreated
1989-11-22
pubmed:abstractText
Doppler echocardiography was used to evaluate left ventricular relaxation and filling in 20 patients on chronic maintenance hemodialysis. In comparison with 11 normal controls hemodialysed patients showed a marked prolongation of isovolumic relaxation period (83 +/- 23 ms vs 67 +/- 11 ms, P less than 0.01). Peak velocity of early diastolic filling was similar in both groups, but peak velocity of late ventricular filling due to atrial contraction was substantially increased in dialysis patients (66 +/- 23 cm/s vs 37 +/- 7 cm/s, P less than 0.01) and the ratio late to early peak velocity was significantly enlarged (0.97 +/- 0.35 vs 0.58 +/- 0.19, P less than 0.01). Although left ventricular mass index, as determined by Echo, was markedly increased in dialysis patients, no significant correlation was found between ventricular mass and indexes of diastolic function. When patients were divided into two groups on the basis of development of hypotension during dialysis clinical and echocardiographic characteristics were similar, although patients with dialysis hypotension (n = 9) were significantly older (53 +/- 9 years) than normotensive patients (n = 11, 42 +/- 14 years, P less than 0.05). Indexes of diastolic function showed a great overlap between the two groups, but ratio late to early peak velocity was significantly greater in patients with intradialytic hypotension (1.13 +/- 0.35 vs 0.83 +/- 0.32, P less than 0.05). It is concluded that dialysis patients exhibit significant alterations of left ventricular relaxation and diastolic filling as assessed by Doppler echocardiography which might be independent of left ventricular hypertrophy. Impaired diastolic function might contribute to intradialytic hypotension.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0023-2173
pubmed:author
pubmed:issnType
Print
pubmed:day
17
pubmed:volume
67
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
826-32
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
Doppler echocardiographic analysis of diastolic left ventricular function in dialysis patients and its relation to intradialytic hypotension.
pubmed:affiliation
Abteilung für Kardiologie, A.O. Krankenhauses der Barmh, Schwestern vom Hl. Kreuz, Wels, Osterreich.
pubmed:publicationType
Journal Article