Linked Life Data

2792856

Source:http://linkedlifedata.com/resource/pubmed/id/2792856

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1989-11-17
pubmed:abstractText
A group of 11 young albino rats was fed with a Mg2+ free diet. After a few days, the animals showed typical signs of Mg2+ deficiency, consisting in skin vasodilation, red conjunctiva and hair loss. Pentylenetetrazol (50 mg/kg i.p.) injected in these rats, 6 and 12 days after the beginning of the diet, elicited a more severe convulsive activity compared with that shown by a control group of 12 rats. These results suggest that a Mg2+ deficiency, though not necessarily responsible for the convulsive activity, may contribute to facilitate an epileptic episode or may lead to more severe convulsions. The possibility of a more powerful activation of the NMDA receptors in Mg2+ deficiency is discussed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0393-5264
pubmed:author
pubmed:issnType
Print
pubmed:volume
4
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
229-34
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:articleTitle
Magnesium deficiency affects the pentylenetetrazol-induced convulsions in magnesium-deprived rats.
pubmed:affiliation
Department of Human Anatomy and Physiology, University of Turin, Italy.
pubmed:publicationType
Journal Article