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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8
|
pubmed:dateCreated |
1989-9-8
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pubmed:abstractText |
Concomitant with a nationwide oral poliovirus vaccine (OPV) campaign in Finland in 1985, an unexpected rise in the number of patients hospitalized with the Guillain-Barré syndrome (GBS) occurred. An analysis based on hospital records covering a population of 1.17 million and 6 years revealed a significantly increased incidence of GBS coinciding with the OPV campaign. We carefully examined 10 cases with onset of GBS within 10 weeks after immunization. Only 4 patients could recall recent symptomatic infection, and we found no specific agent in these cases. Our study suggests that live-attenuated polioviruses may, like other infectious viruses, sometimes trigger the GBS.
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pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Aug
|
pubmed:issn |
0028-3878
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
39
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
|
pubmed:pagination |
1034-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2788248-Adolescent,
pubmed-meshheading:2788248-Adult,
pubmed-meshheading:2788248-Aged,
pubmed-meshheading:2788248-Cohort Studies,
pubmed-meshheading:2788248-Female,
pubmed-meshheading:2788248-Finland,
pubmed-meshheading:2788248-Humans,
pubmed-meshheading:2788248-Male,
pubmed-meshheading:2788248-Middle Aged,
pubmed-meshheading:2788248-Poliomyelitis,
pubmed-meshheading:2788248-Poliovirus Vaccine, Oral,
pubmed-meshheading:2788248-Polyradiculoneuropathy,
pubmed-meshheading:2788248-Time Factors,
pubmed-meshheading:2788248-Vaccination
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pubmed:year |
1989
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pubmed:articleTitle |
Incidence of Guillain-Barré syndrome during a nationwide oral poliovirus vaccine campaign.
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pubmed:affiliation |
Institute of Occupational Health, Department of Neurology, Helsinki, Finland
|
pubmed:publicationType |
Journal Article,
Comparative Study
|