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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1989-9-19
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pubmed:abstractText |
Anti-Ro/SSA antibodies were determined by a newly developed enzyme-linked immunosorbent assay in serum specimens from 114 patients with systemic scleroderma in order to examine the relationship between Ro/SSA antibodies and clinical subsets of scleroderma. Sera of 42 patients (37%) were positive for Ro/SSA antibodies. Clinical investigations, including Schirmer's test and enzymatic profiles, demonstrated that 60% (16 of 27) of scleroderma patients with sicca syndrome and 63% (10 of 16) with polymyositis (PM) were Ro/SSA positive. In these patients there was a significant association between Ro/SSA antibodies and rheumatoid factor. HLA-antigens DR2, DR3 and B8 showed an increased frequency in anti-Ro/SSA positive patients.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0007-0963
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
121
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
35-41
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:2788010-Antibodies, Antinuclear,
pubmed-meshheading:2788010-Autoantibodies,
pubmed-meshheading:2788010-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:2788010-Female,
pubmed-meshheading:2788010-HLA Antigens,
pubmed-meshheading:2788010-Humans,
pubmed-meshheading:2788010-Male,
pubmed-meshheading:2788010-Middle Aged,
pubmed-meshheading:2788010-Scleroderma, Systemic
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pubmed:year |
1989
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pubmed:articleTitle |
Antibodies to Ro/SSA detected by ELISA: correlation with clinical features in systemic scleroderma.
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pubmed:affiliation |
Department of Dermatology, Ludwig-Maximilians-Universität, Munich, F.R.G.
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pubmed:publicationType |
Journal Article
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