Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
|
pubmed:dateCreated |
1989-8-18
|
pubmed:abstractText |
There was no overall increase in PB-CFU-GM from normal subjects, or MDS patients, when exogenous CSA (5637-CM) was added to the culture medium. However, there was a sub-group of MDS patients (seven of 35) whose PB-CFU-GM numbers were significantly stimulated by 5637-CM. In addition, there were 11 (out of 48) MDS patients with undetectable PB-CFU-GM in assays without exogenous CSA but only two when 5637-CM was added (p less than 0.01). This sub-group is of particular interest as it is known that those without detectable PB-CFU-GM tend to have significantly shorter survival times than others. The mechanism of the functional abnormality is yet to be determined.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0145-2126
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
13
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
385-9
|
pubmed:dateRevised |
2004-11-17
|
pubmed:meshHeading |
pubmed-meshheading:2787448-Aged,
pubmed-meshheading:2787448-Cell Division,
pubmed-meshheading:2787448-Cells, Cultured,
pubmed-meshheading:2787448-Colony-Stimulating Factors,
pubmed-meshheading:2787448-Culture Media,
pubmed-meshheading:2787448-Female,
pubmed-meshheading:2787448-Granulocytes,
pubmed-meshheading:2787448-Hematopoietic Stem Cells,
pubmed-meshheading:2787448-Humans,
pubmed-meshheading:2787448-Leukocyte Count,
pubmed-meshheading:2787448-Macrophages,
pubmed-meshheading:2787448-Male,
pubmed-meshheading:2787448-Middle Aged,
pubmed-meshheading:2787448-Myelodysplastic Syndromes,
pubmed-meshheading:2787448-Prognosis
|
pubmed:year |
1989
|
pubmed:articleTitle |
Effect of 5637-conditioned medium on peripheral blood granulocyte-macrophage progenitors in normal subjects and patients with the myelodysplastic syndrome.
|
pubmed:affiliation |
Department of Haematology, University of Wales College of Medicine, Cardiff, U.K.
|
pubmed:publicationType |
Journal Article
|